A: quantification of newborn and adult liver IGF1 peptide relative to GAPDH and expressed as a percentage of AdLib (newborn) and AdLib/Adlib (adult). Newborn open bar represents AdLib, and solid bars represent FR; adult open bars represent AdLib/AdLib (control), solid bars represent FR/AdLib (FR during pregnancy), and hatched bar represents FR/FR (FR during pregnancy and lactation); asterisk denotes differences between AdLib and FR newborns; a and b denote a significant difference between the adult groups AdLib/AdLib, FR/AdLib, and FR/FR, P < 0.05. B: newborn and adult plasma IGF1 concentrations (ng/ml). Newborn open bar represents AdLib, and solid bars represent FR; adult open bar represents AdLib/AdLib (control), solid bar represents FR/AdLib (FR during pregnancy), and hatched bar represents FR/FR (FR during pregnancy and lactation); asterisk denotes differences between AdLib and FR newborns, P < 0.01; a and b denote a significant difference between the adult groups AdLib/AdLib, FR/AdLib, and FR/FR, P < 0.05.