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Effect of dietary protein on signal transduction pathway activation in the pancreas of CCK-null mice. Changes in the phosphorylation of p42/44 ERK (A) and the calcineurin substrate CRHSP-24 (B) after feeding normal-protein or high-protein chow. Fast, food deprived for 16 h; NP, refed 140 g/kg casein chow for 2 h; HP, refed 750 g/kg casein chow for 2 h; NP+TI, C57Bl/6 mouse refed 140 g/kg casein chow supplemented with 0.1% trypsin inhibitor for 2 h.
