Fig. 6.

Effect of rapamycin administration on pancreatic growth in CCK-null mice. Changes in pancreas weight (A), protein content (B), DNA content (C), and RNA content (D) in mice fed normal- or high-protein diet and administered vehicle or rapamycin for 7 days. Values represent means ± SE; n = 9–11 mice. *Significantly different from normal protein diet (protein effect); †significantly different from vehicle-treated value (rapamycin effect), 1 symbol P < 0.05; 2 symbols P < 0.01 as determined by 2-way ANOVA.