Fig. 8.

Effect of dietary protein on pancreatic morphology in postabsorptive CCK-null mice. Semithin plastic sections stained with toluidine blue of Epon-embedded pancreatic tissue from mice fed 140 g/kg casein chow for 7 days (A), 750 g/kg casein chow for 7 days (B), 140 g/kg casein chow for 7 days while administered daily intraperitoneal (IP) injections of rapamycin (C), and 750 g/kg casein chow for 7 days while administered daily IP injections of rapamycin (D). Ultrathin sections stained with uranyl acetate and lead citrate of Epon embedded pancreatic tissue from mice fed 140 g/kg casein chow for 7 days while administered daily IP injections of rapamycin (E) and 750 g/kg casein chow for 7 days while administered daily IP injections of rapamycin (F). Arrows point to acinar lumens; arrowheads point to vacuoles.