Figure 3. Kinetics of antigen-specific CD8 T cell response induced by Salmonella vaccine alone and in combination with NKT ligand.
(A) Mice were administrated with either MvP728-vector, MvP728-Llo vaccine, or MvP728-Llo with GSL1. Boost vaccination was given on days 14 and 28 without GSL1. Blood was collected on days 10, 21, and 36, leukocytes were stained for CD8 and Llo-specific TCR expression. Shown are representative plots with numbers indicating percent Llo-specific CD8 T cells. (B) Means ± SD of Llo-specific CD8 T cells at indicated time points after vaccination from three experiments. **P<0.01, ***P<0.001, one-way ANOVA.