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. Author manuscript; available in PMC: 2011 Nov 7.
Published in final edited form as: Phys Med Biol. 2010 Oct 12;55(21):6395–6410. doi: 10.1088/0031-9155/55/21/004

Table 1.

List of parameters and variables.

Label Definition (typical value)

Constraints
Tmax maximum allowable temperature (5.25 °C)
Tz desired peak temperature in a treatment zone (5 °C)
tp pulse length (period = tp/dc) (50 ms)
M number of treatment zones (4-6)
m number of focal spots per treatment zone (8)
tq time of mechanical motion (30 s); q = tq/tp
N total number of pulses per focal spot (100)

Variables & Symbols

T temperature
dc device duty cycle
DCz local ‘treatment zone’ duty cycle
DCN net duty cycle
nz pulses per focal spot in a single pass
n pulse number, from 0 to N
theat = mnztp/dc time spent treating (heating) a single treatment zone
tM = M (mnztp/dc + tq) time required to treat M treatment zones
tcool = tMtheat time between treatments of a single treatment zone
Δ increase in Tmax over Tz: Δ=TmaxTzTz