Table 3.
Variable* | All primary and metastatic melanomas
|
High-risk melanomas (thickness > 1.5 mm)
|
||||
---|---|---|---|---|---|---|
Relative risk | 95% CI† | P value | Relative risk | 95% CI† | P value | |
Overall survival | ||||||
Sox4 | 1.571 | 0.924–2.673 | 0.095 | 1.904 | 1.078–3.362 | 0.026 |
Age | 0.676 | 0.407–1.122 | 0.122 | 0.974 | 0.574–1.650 | 0.922 |
Sex | 1.238 | 0.736–2.084 | 0.419 | 1.075 | 0.606–1.906 | 0.802 |
Disease-specific survival | ||||||
Sox4 | 1.780 | 1.001–3.163 | 0.049 | 1.994 | 1.087–3.658 | 0.025 |
Age | 1.780 | 0.540–1.662 | 0.850 | 1.337 | 0.753–2.373 | 0.320 |
Sex | 1.100 | 0.618–1.958 | 0.744 | 1.011 | 0.547–1.870 | 0.970 |
Coding of variables: Sox4 nuclear staining was coded as 1 (negative-weak) and 2 (moderate-strong). Age was coded as 1 (≤58 years), and 2 (>58 years). Gender was coded as 1 (female) and 2 (male).
CI: confidence interval.