Table 2.
Overlap between Genotype and Histologic Types of Low-Grade Diffuse Gliomas (WHO Grade II)
Genotype | Histologically diagnosed as
|
||
---|---|---|---|
Diffuse astrocytoma | Oligoastrocytoma | Oligodendroglioma | |
TP53 mutation ± IDH1/2 mutation (n = 121) | 90 (74%) | 22 (18%) | 9 (7%) |
1p/19q loss ± IDH1/2 mutation (n = 145) | 26 (18%) | 25 (17%) | 94 (65%) |
IDH1/2 mutation only (n = 61) | 40 (66%) | 12 (20%) | 9 (15%) |
No genetic alteration (n = 26) | 15 (58%) | 2 (8%) | 9 (35%) |