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. 2010 Dec;177(6):2708–2714. doi: 10.2353/ajpath.2010.100680

Table 2.

Overlap between Genotype and Histologic Types of Low-Grade Diffuse Gliomas (WHO Grade II)

Genotype Histologically diagnosed as
Diffuse astrocytoma Oligoastrocytoma Oligodendroglioma
TP53 mutation ± IDH1/2 mutation (n = 121) 90 (74%) 22 (18%) 9 (7%)
1p/19q loss ± IDH1/2 mutation (n = 145) 26 (18%) 25 (17%) 94 (65%)
IDH1/2 mutation only (n = 61) 40 (66%) 12 (20%) 9 (15%)
No genetic alteration (n = 26) 15 (58%) 2 (8%) 9 (35%)