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. 2010 Dec;177(6):2963–2970. doi: 10.2353/ajpath.2010.100375

Figure 2.

Figure 2

Effect of WIN 55212-2 on cell proliferation and cell viability. A: Proliferative rate of each stromal endometriotic cell line (11 eutopic endometrial stromal cell lines, Es, and 14 deep infiltrating endometriotic stromal cell lines, Ds) and of three control endometrial stromal cell lines (Cs) treated in vitro with increasing concentrations (0.3–40 μmol/L) of WIN 55212-2. Black dotted line shows the basal level of proliferation of untreated endometriotic cells. Cell proliferation was determined by thymidine incorporation. Results are expressed as ratios of treated versus untreated cells: *P < 0.05. B: Cell viability of each stromal endometriotic cell line (11 eutopic endometrial stromal cell lines, Es, and 14 deep infiltrating endometriotic stromal cell lines, Ds) and of three control endometrial stromal cell lines (Cs) untreated or treated in vitro with increasing concentrations (0.3 to 40 μmol/L) of WIN 55212-2. Analysis by Hoechst 33342 staining. Fluorescence intensity was recorded with a fluorescence excitation/emission maxima of 350/461 nm.