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. 2010 Dec;177(6):2827–2836. doi: 10.2353/ajpath.2010.100368

Figure 3.

Figure 3

HFD-fed Grp78+/− mice gained similar weight as wild types. A: Scheme of high-fat diet (HFD) feeding. Cohorts of Grp78+/+ and +/− male littermates were fed a RD after weaned at 3 weeks of age, and switched to HFD feeding from 10 weeks of age. B: Fasting body weight. n ≥ 5 mice per condition. *P < 0.05, **P < 0.01 for HFD versus RD. C: Food intake measurement during the 10th week of HFD. n = 9 mice for each genotype. Data are presented as the mean ± SEM. D: Oil Red O staining of stool smear from mice during the 20th week of HFD. Negative control, dH2O; positive control, white adipose extract. n = 3 (+/+) or 4 (+/−).