Table 3.
Compiled grades 3 and 4 nonhematologic toxicities (N = 23)
| Event | Grade 3 | Grade 4 |
|---|---|---|
| Constitutional | ||
| Fatigue | 7 | 0 |
| Dermatologic | ||
| Rash/erythema | 1 | 0 |
| Gastrointestinal | ||
| Anorexia | 6 | 0 |
| Diarrhea | 2 | 0 |
| Dysphagia | 1 | 0 |
| Esophagitis | 1 | 0 |
| Mucositis | 1 | 0 |
| Nausea | 3 | 0 |
| Infection | ||
| Febrile neutropenia | 10 | 0 |
| Infection w/neutropenia | 12 | 0 |
| Metabolic | ||
| Aspartate amino transferase | 3 | 0 |
| Musculoskeletal | ||
| Myositis | 1 | 0 |
| Neurology | ||
| Anxiety | 1 | 0 |
| Ataxia | 3* | 0 |
| Somnolence | 1 | 0 |
| Pain | ||
| Headache | 1 | 0 |
| Pleura | 2 | 0 |
| Pulmonary | ||
| Hypoxia | 1 | 0 |
| Pneumonitis/infiltrates | 5 | 0 |
*
Dose-limiting toxicity.