FIG. 1.

A: Location of the fragment introgressed to generate the NOD-Alox15^null congenic strain. Black intervals represent confirmed homozygosity for B6;129S2 from the donor B6,129S2-Alox15^tm1Fun strain; light gray intervals are indeterminate regions containing recombination end points for the congenic interval; and white intervals are regions derived from the congenic background strain. B: Intervals defining sub-loci for Idd4 in congenic mouse strains. a: Map of NOD-Alox15^null mice (this report). b: Composite map from NOD-Idd4A and NOD-Idd4B (7), showing localization of Idd4.1 and Idd4.2. c: Composite map of NOD contributions to informative NOR.NOD-Idd4R3 and NOR.NOD-Idd4R3 congenic lines (42). d: Map of NOD.Lc11b, showing localization of Idd4.3 (6). Black intervals represent confirmed homozygosity for donor alleles: B6;129S2 in panel a, B6 in panel b, NOD in panel c; white intervals, regions derived from the congenic background strain; light gray intervals, indeterminate regions containing recombination end points. In panel c, dark gray intervals represent known NOD-derived regions in informative congenic lines.