FIG. 4.

Aldehyde fuchsin staining of the islets. Fourteen nondiabetic female NOD-Alox15^null mice and 10 nondiabetic NOD females were evaluated for insulitis and β-cell granulation at 30 weeks of age. Pancreata were stained with aldehyde fuchsin and evaluated by standard light microscopy. A: Representative section showing a well-preserved islet in a NOD-Alox15^null mouse. B: A representative example of an infiltrated islet seen in an age-matched nondiabetic NOD mouse.