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A–C, HEK293 cells stably transfected with ABCC4 cDNA and parental HEK293 cells were transfected with an NT5E/CD73 construct or with empty vector. Levels of extracellular TGMP and TGrib and intracellular 6-TGNs were determined after treatment with 5 μM 6-TG. D, cytotoxicity after incubation of the same cells with 5 μM 6-MP or 5 μM 6-TG.
