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. 2010 Dec;38(12):2329–2338. doi: 10.1124/dmd.110.035220

TABLE 2.

Correlations between thiopurine pathway gene expression and levels of 6-TGNs in 16 randomly selected cell lines after 6-TG treatment

Data for genes listed more than once represent results for different expression array probesets. Many genes had multiple probesets on the array. The data have been ordered by p values from lowest to highest.

Gene Chromosome Probe Set p Value Spearman Correlation
TPMT 6 203672_x_at 0.0002 −0.80
NT5E 6 203939_at 0.0064 0.65
ABCC4 13 203196_at 0.0078 −0.64
SLC29A1 6 201802_at 0.0100 −0.61
NT5E 6 1553995_a_at 0.0108 0.62
ABCC5 3 209380_s_at 0.0273 −0.55
GART 21 212378_at 0.0283 −0.55
PPAT 4 209433_s_at 0.0350 −0.53
ADK 10 204119_s_at 0.0441 −0.51
GART 21 212379_at 0.0602 −0.48
ABCC5 3 226363_at 0.1130 0.41
PPAT 4 209434_s_at 0.1290 −0.40
HPRT1 X 202854_at 0.1577 −0.37
IMPDH1 7 204169_at 0.2168 0.33
TPMT 6 203671_at 0.2172 −0.33
GART 21 217445_s_at 0.2541 −0.30
ADK 10 204120_s_at 0.2589 −0.30
ABCC4 13 1554918_a_at 0.2999 −0.28
ABCC4 13 1555039_a_at 0.3622 −0.24
GART 21 210005_at 0.3743 −0.24
GART 21 216990_at 0.4035 −0.22
ADA 20 216705_s_at 0.5204 0.17
XDH 2 210301_at 0.5276 0.17
AOX1 2 205082_s_at 0.5554 0.16
SLC29A1 6 201801_s_at 0.6900 0.11
IMPDH2 3 201892_s_at 0.7125 0.10
AHCY 20 200903_s_at 0.7207 −0.10
AOX1 2 205083_at 0.7969 0.07
PRPS1 X 209440_at 0.8541 −0.05
ITPA 20 209171_at 0.8968 −0.04
ADA 20 204639_at 0.9139 0.03
GMPS 3 214431_at 0.9139 0.03