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The modification of and PNU-120596's potentiation on α7 C116S after DTT treatment. A, representative traces illustrating the strong agonist activity of MTSET, QN-SH, and Br-ACh for 5-min DTT-treated α7 C116S, and the induction of a PNU-120596-sensitive desensitization. B, the SH reagent and PNU-120596 activation of DTT-treated α7 C116S relative to the average of two ACh controls before DTT treatment. The data represent the average responses of at least four oocytes (± S.E.M.).
