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UCL2077 inhibits the sAHP in mouse hippocampus. A, top, representative sAHP recording from a CA1 pyramidal neuron induced by a 300 ms, 1 nA current pulse before (black) and after (gray) application of 10 μM UCL2077. Bottom, representative sAHP recording from a CA3 pyramidal neuron induced by a 100-ms, 1-nA current pulse before (black) and after (gray) application of 10 μM UCL2077. B, graph summarizing the sAHP block induced by 10 μM UCL2077.
