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. Author manuscript; available in PMC: 2010 Nov 29.
Published in final edited form as: Immunol Today. 1996 Dec;17(12):577–588. doi: 10.1016/s0167-5699(96)10070-0

Fig 1.

Fig 1

(Upper panels) One-way paradigm in which transplantation is conceived as involving a unidirectional immune reaction: (a) host-versus-graft (HVG) with whole organs and (b) graft-versus-host (GVH) with bone marrow or other lymphopoietic transplants. (Lower panels) Two-way paradigm in which transplantation is seen as a bidirectional and mutually cancelling immune reaction that is (c) predominantly HVG with whole organ grafts, and (d) predominantly GVH with bone marrow grafts.