Table 5.

Pathological Findings^* in the Small Bowel Grafts Following a 2-Week Course of FK 506

Strain Combination		Pathological Findings of the Graft
Recipient	Donor	Mucosa†	Peyer’s Patches‡	Mesenteric Lymph Nodes‡	Obliterative Arteriopathy
BN	LEW	0	0	0	0
BN	PVG	0	0	0	0
BN	ACI	1	2	1–2	0–2
LEW	ACI	1	2	2	0–1
LEW	BN	1	1	2	0–1
LEW	PVG	0	1–2	1	0–2
PVG	LEW	0	0	0–1	0
PVG	ACI	0	0	0–1	0
PVG	BN	0	0	0–1	0
ACI	LEW	0	0	0	0
ACI	BN	0	0	0	0
ACI	PVG	0	0	0	0

^*Tissues from animals who died before 150 days or those surviving 150 to 506 days after small bowel transplantation.

^†Blunting of villi, cryptitis, and lymphoid depleted lamina propria.

^‡Lymphoid depletion and fibrosis.

Diagnosis was classified histologically as 0, nothing ~ rare; 1, present; 2, severe. Two to four animals were examined in each donor-recipient combination.