Table 2.
Conservation of aerial mycelium and spore formation-related genes in K. setae NBRC 14216T and other mycelial actinobacteria
| Kitasatospora setae NBRC 14216Ta | Streptomyces coelicolor A3(2) | Streptomyces avermitilis MA-4680T | Streptomyces griseus IFO 13350 | Streptomyces scabies 87.22 | Catenulispora acidiphila DSM 44928 | Saccharopolyspora erythraea NRRL 23338 | Salinispora arenicola CNS 205 | |
|---|---|---|---|---|---|---|---|---|
| Aerial mycelium | ||||||||
| bldA | KSE_t0069 | SCOt24 | SAV_t57 | SGR_tRNA42 | SCAB_t50 | Caci_R0007 | SACE_8016 | Sare_R0014 |
| bldB | (KSE_16220)b (64) | SCO5723 (SCO7246) | SAV_2529 (SAV_1241) | SGR_1796 | SCAB_25271 (SCAB_84941) | ND | SACE_6156 | Sare_3856 |
| bldC | KSE_41620 (97) | SCO4091 | SAV_4130 | SGR_3882 | SCAB_47901 | Caci_0301 | SACE_6926 | Sare_0170 |
| bldD | KSE_13950 (92) | SCO1489 | SAV_6861 | SGR_6045 | SCAB_75171 | Caci_2399 | SACE_2077 | Sare_1844 |
| bldG (=rsbV) | KSE_35840 (96) | SCO3549 | SAV_4614 | SGR_3307 | SCAB_40861 | Caci_8450 | SACE_4194 | Sare_4413 |
| bldH (=adpA) | KSE_26930 (80) | SCO2792 | SAV_5261 | SGR_4742 | SCAB_57831 | Caci_5972 | SACE_4523 | ND |
| bldKA-bldKE | KSE_48250–KSE_48290 (41–78) | SCO5112–SCO5116 | SAV_3152–SAV_3156; SAV_3172–SAV_3176 | SGR_2414–SGR_2418 | SCAB_31501–SCAB_31541 | Caci_7147–Caci_7151 | ND | ND |
| bldM (=whiK) | KSE_31060 (97) | SCO4768 | SAV_4998 | SGR_2759 | SCAB_36231 | Caci_1011 | SACE_6712 | Sare_4229 |
| bldN (=adsA) | KSE_33690 (92) | SCO3323 | SAV_4735 | SGR_4151 | SCAB_39121 | Caci_8330 | SACE_6951 | Sare_0420 |
| amfC | KSE_43740 (54) | SCO4184 | SAV_4026 | SGR_3974 | SCAB_49711 | Caci_8239 | SACE_7115 | ND |
| Lantibiotic-like surfactant | ||||||||
| amfR (=ramR) | ND | SCO6685 | SAV_7499 | SGR_2393 | SCAB_8642c | ND | ND | ND |
| amfS (=ramS) | ND | SCO6682 | SAV_7502 | SGR_2396 | SCAB_8621 | Caci_4240 | SACE_4231 | ND |
| amfB (=ramA) | ND | SCO6683 | SAV_7501 | SGR_2395 | SCAB_8631 | Caci_4242 | SACE_4232 | ND |
| amfA (=ramB) | ND | SCO6684 | SAV_7500 | SGR_2394 | SCAB_8641 | Caci_4243 | SACE_4233 | ND |
| amfT (=ramC) | KSE_63000 (44) | SCO6681 | SAV_7503 | SGR_2397 | SCAB_8611 | Caci_4239 | SACE_4230 | ND |
| Sporulation | ||||||||
| whiA | KSE_55390 (89) | SCO1950 | SAV_6294 | SGR_5572 | SCAB_69681 | Caci_5609 | SACE_2141 | Sare_3326 |
| whiB | KSE_29410 (83) | SCO3034 | SAV_5042 | SGR_4503 | SCAB_55081 | Caci_7609 | SACE_6464 | ND |
| whiD (=wblB) | KSE_31070 (90) | SCO4767 | SAV_4997 | SGR_2760 | SCAB_36241 | Caci_1009 | SACE_5583 | ND |
| whiE | KSE_72410–KSE_72480 (46–67) | SCO5314–SCO5321 | SAV_2837–SAV_2844 | ND | SCAB_43281–SCAB43341 | Caci1083–Caci1090 | ND | Sare_2682–Sare_2690 |
| whiG | KSE_52540 (79) | SCO5621 | SAV_2630 | SGR_1866 | SCAB_26051 | Caci_1526 | SACE_6040 | ND |
| whiH | KSE_54050 (74) | SCO5819 | SAV_2445 | SGR_1702 | SCAB_24461 | Caci_1760 | ND | ND |
| whiI | KSE_55090 (77) | SCO6029 | SAV_2230 | SGR_1475 | SCAB_20881 | Caci_6781 | SACE_1833 | ND |
| sigF | KSE_37310 (69) | SCO4035 | SAV_4185 | SGR_3551 | SCAB_47291 | Caci_7708 | ND | ND |
| sigN | KSE_37320 (80) | SCO4034 | SAV_4186 | SGR_3552 | SCAB_47281 | ND | ND | ND |
| crgA (=whiP) | KSE_39340 (50) | SCO3854 | SAV_4331 | SGR_3718 | SCAB_45631 | Caci_0043 | SACE_0037 | Sare_0058 |
aThe amino acid identity between K. setae NBRC 14216T ORF and S. coelicolor A3(2) ortholog was shown in parentheses. The range of amino acid identity was shown where multiple genes were assigned.
bbldB gene paralog found in S. coelicolor A3(2) and S. avermitilis MA-4680T are also included. KSE_16220 corresponds to an ortholog of the bldB paralog.
cThis ORF tentatively named SCAB_8642 (corresponding to position 975 194–975 802 on the complementary strand) has not yet been incorporated in the submitter annotation.