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(A) Representative tracing of the computer generated swimming pattern of a mouse placed in a large water bath (diameter 122 cm) for 5 minutes. White squares represent starting and ending positions. (B and C) Graphical representation of the average (B) swimming velocity and (C) distance of WT and RyR2-S2808A+/+ mice over the course of 5 minutes (WT, n = 17; RyR2-S2808A+/+, n = 18; *P < 0.05).
