Table 3.

Plaque phenotypic characteristics of established atherosclerosis

	Baseline	Cd40l+/+Apoe−/−	Cd40l−/−Apoe−/−	Vehicle
% CD3	0.2 ± 0.1	3.4 ± 0.6	3.4 ± 0.4	2.0 ± 0.4
% CD45	2.9 ± 0.9	4.6 ± 0.8	5.2 ± 0.5	2.6 ± 0.2
% Mac3	42.1 ± 6.6	44.5 ± 2.8	58.8 ± 5.1	62.5 ± 5.2
MAC-3 Abs	81.8 ± 38.6	385.6 ± 52.2	310.9 ± 63.8	363.5 ± 84.2
Caspase-3+	0.1 ± 0.1	1.3 ± 0.3	1.4 ± 0.4	0.9 ± 0.3
% α-SMA	0.0 ± 0.0	11.3 ± 1.3	11.4 ± 1.0	11.0 ± 0.5
% SR	1.1 ± 0.9	34.2 ± 5.9	19.0 ± 5.6*	23.2 ± 5.9
% LC	0.0 ± 0.0	7.9 ± 2.5	5.1 ± 1.5	3.7 ± 1.6

^*P < .05 vs Cd40l^+/+Apoe^−/−.