Figure 2.

Relative concentrations of SmCB1-specific immunoglobulin isotypes in plasma of mice with pre-patent schistosome infection. SmCB1-specific IgM (A), IgG1 (B), IgG2b (C) and IgE (D) in the plasma of wild type mice with pre-patent (2, 3 and 4 weeks post infection) and patent infection (8 weeks post infection) were quantified by ELISA. Data are displayed as relative fluorescence units (RFU) for IgM (A), IgG1 (B) and IgG2b (C), and as relative absorbance units (RAU) for IgE (D). P values for the first time points to show significant increases in antibody level are shown (obtained by Dunn's post-test following Kruskal-Wallis test). Experimental groups consisted of five mice per group. Data are representative of three independent experiments.