Table 1.
Characteristics of each participant subgroup
| Whole group (N = 63) | MRI subset (N = 34) | |||||
|---|---|---|---|---|---|---|
| C | RPD | LPD | C | RPD | LPD | |
| n | 28 | 19 | 16 | 15 | 11 | 8 |
| Age in years | 54.1 (14.0) | 59.3 (12.0) | 57.5 (11.0) | 57.7 (10.2) | 56.5 (10.6) | 55.3 (11.5) |
| Male/female ratio | 13/15 | 8/11 | 10/6 | 5/10 | 3/8 | 5/3 |
| Education level in years | 14.8 (2.8) | 15.5 (2.7) | 14.8 (2.8) | 14.3 (2.7) | 15.8 (2.9) | 14.0 (3.0) |
| WRAT-3R | 107.0 (6.8) | 107.4 (6.9) | 101.4 (13.1) | 104.7 (5.8) | 107.3 (7.9) | 99.5 (14.1) |
| Verbal fluency | 42.8 (13.8) | 39.8 (16.6) | 42.6 (15.2) | 46.0 (13.8) | 45.3 (15.4) | 47.5 (16.8) |
| Medication status | ||||||
| Treated/naïve | — | 13/6 | 13/3 | — | 10/1 | 8/0 |
| On/off (at testing) | — | 10/9 | 8/8 | — | 7/4 | 7/1 |
| Duration of disease in years | — | 4.5 (3.6) | 4.1 (4.4) | — | 5.9 (4.1) | 6.4 (5.3) |
| UPDRSm | — | 22.1 (10.9) | 20.3 (8.9) | — | 24.6 (12.9) | 23.7 (8.0) |
| Symptom score | ||||||
| Tremor | — | 3.8 (2.9) | 2.2 (2.1) | — | 4.5 (3.3) | 3.1 (2.5) |
| Rigidity | — | 4.4 (2.7) | 4.7 (2.8) | — | 4.4 (2.8) | 4.5 (3.2) |
| Bradykinesia | — | 8.3 (4.7) | 7.6 (3.3) | — | 9.4 (5.4) | 9.0 (3.3) |
| Motor asymmetry score | — | 0.67 (0.54) | −0.78 (0.45) | — | 0.66 (0.48) | −0.61 (0.15) |
| SN volume (cm3) | ||||||
| Right SN | — | — | — | 0.53 (0.08) | 0.51 (0.08) | 0.45 (0.09) |
| Left SN | — | — | — | 0.53 (0.09) | 0.53 (0.05) | 0.47 (0.10) |
| SN asymmetry score | — | — | — | 0.01 (0.18) | −0.04 (0.07) | −0.03 (0.13) |
Numbers represent means (standard deviation) or number of participants.
C, control; RPD, PD participants with worse right-sided symptoms; LPD, PD participants with worse left-sided symptoms; WRAT-3R, wide range achievement test III reading task standard score; UPDRSm, unified Parkinson’s disease rating scale, motor subscore; SN, substantia nigra.