Figure 4.

Comparison of the accuracy in peak size quantification between the bi-Gaussian mixture model and the method of kernel smoother combined with signal summation. Each sub-plot corresponds to a different degree of asymmetry, as shown in the titles of the sub-plots (ratios between the right- and left- standard deviations). Each dot represents a simulated situation. The values were obtained by averaging the results from 100 simulations. The color represents the level of overlaps between the simulated peaks. The size of the dot represents the amount of noise added to the data. The fill of the dot represents the percentage of values missing in the ion trace.