Table 2.
Means of HPV viral loads according to selected characteristics at the first occurrence of positivity for a given HPV type
| HPV 16 | HPV 18 | HPV 31 | HPV 45 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic* | N | Mean | 95% CI | N | Mean | 95% CI | N | Mean | 95% CI | N | Mean | 95% CI |
| Age | ||||||||||||
| <25 years | 72 | 0.47 | 0.19-1.19 | 32 | 0.93 | 0.18-4.96 | 31 | 2.07 | 0.54-7.97 | 14 | 0.26 | 0.03-2.62 |
| 25+ years | 31 | 0.21 | 0.05-1.01 | 11 | 0.08 | 0.03-0.46 | 5 | 0.45 | 0.04-5.33 | 5 | 0.09 | 0.01-8.02 |
| Coinfection, other HPVs | ||||||||||||
| None # | 10 | 0.17 | 0.02-1.24 | 5 | 0.05 | 0.01-0.25 | 4 | 1.88 | 0.10-35.6 | 3 | 0.09 | 0.01-8.03 |
| Sequential | 56 | 0.56 | 0.18-1.70 | 21 | 1.61 | 0.14-18.18 | 17 | 1.29 | 0.12-14.1 | 8 | 0.06 | 0.00-3.37 |
| Concurrent | 38 | 0.25 | 0.06-0.93 | 17 | 0.62 | 0.05-7.09 | 15 | 1.76 | 0.29-10.9 | 8 | 0.41 | 0.00-18.58 |
| Smoking | ||||||||||||
| Never | 60 | 0.34 | 0.11-1.04 | 23 | 0.16 | 0.02-1.05 | 22 | 0.66 | 0.09-4.49 | 11 | 0.17 | 0.03-8.28 |
| Current | 25 | 0.79 | 0.21-2.91 | 15 | 1.29 | 0.18-9.36 | 8 | 1.80 | 0.38-8.56 | 3 | 0.32 | 0.05-2.46 |
| Former | 18 | 0.13 | 0.02-1.07 | 5 | 3.86 | 0.04-37.47 | 6 | 21.87 | 2.26-211.3 | 5 | 0.17 | 0.03-11.18 |
| Condom use | ||||||||||||
| No | 15 | 0.09 | 0.01-1.05 | 10 | 0.72 | 0.01-44.43 | 4 | 0.49 | 0.02-122. | 3 | 0.03 | 0.003-2.48 |
| Used sometimes | 44 | 0.78 | 0.21-2.82 | 17 | 0.35 | 0.04-3.34 | 13 | 6.09 | 0.70-53.1 | 12 | 0.33 | 0.02-6.19 |
| Regular use | 39 | 0.51 | 0.17-1.48 | 15 | 0.72 | 0.08-6.92 | 16 | 1.01 | 0.15-6.68 | 5 | 0.22 | 0.02-16.23 |
| Oral contraceptive use | ||||||||||||
| No | 23 | 0.28 | 0.04-1.80 | 13 | 0.22 | 0.02-2.18 | 10 | 0.51 | 0.04-2.09 | 7 | 0.13 | 0.01-1.57 |
| Infrequent | 63 | 0.42 | 0.16-1.08 | 25 | 0.69 | 0.13-3.65 | 21 | 0.91 | 0.19-4.34 | 10 | 0.46 | 0.02-9.44 |
| Regular | 7 | 1.10 | 0.18-67.6 | 4 | 1.92 | 1.3-3.82 | 4 | 7.4 | 2.08-26.7 | 2 | 0.98 | 0.01-54.21 |
| Sexual partners | ||||||||||||
| One | 5 | 0.05 | 0.01-6.12 | 5 | 0.02 | 0.04-9.03 | 2 | 0.80 | 0.03-205. | 5 | 0.06 | 0.01-3.60 |
| 2-3 | 24 | 0.72 | 0.16-3.16 | 7 | 2.30 | 0.04-146.1 | 13 | 3.32 | 0.31-34.9 | 2 | 0.06 | 0.005-6.57 |
| 4+ | 75 | 0.34 | 0.14-0.90 | 31 | 0.59 | 0.13-2.62 | 21 | 1.09 | 0.23-5.04 | 12 | 0.41 | 0.03-5.61 |
* Defined at the time of first occurrence of positivity for the stated HPV type.
# Concurrent coinfection defined as the detection of more than one HPV type in the cervical cell specimen collected at the first visit when the stated type was found. Sequential coinfection defined as additional HPV types detected at different visits than the one when the stated type was found.