Table 3.
Relative rate (95%CI) | ||||
---|---|---|---|---|
HPV type | Viral load tertile | No. of Events/No. Eligible cases | Unadjusted | Adjusted |
16 | Third | 5/27 | 1.0 | 1.0 |
Second | 8/27 | 1.52 (0.49-4.69) | 1.31 (0.41-4.20) | |
First | 13/27 | 2.55 (0.90-7.24) | 2.38 (0.82-6.89) | |
18 | Third | 4/13 | 1.0 | 1.0 |
Second | 3/13 | 1.64 (0.31-8.78) | 1.14 (0.18-7.35) | |
First | 11/13 | 4.76 (1.23-18.45) | 4.61 (1.17-18.05) | |
31 | Third | 6/10 | 1.0 | 1.0 |
Second | 3/10 | 0.87 (0.21-3.69) | 0.80 (0.19-3.44) | |
First | 2/9 | 0.67 (0.16-2.75) | 0.66 (0.15-2.97) | |
45 | Third | 3/6 | 1.0 | 1.0 |
Second | 4/6 | 1.99 (0.21-19.02) | 1.59 (0.15-16.91) | |
First | 3/6 | 2.25 (0.20-25.09) | 2.06 (0.17-24.27) | |
Above HPV types combined | Third | 20/55 | 1.0 | 1.0 |
Second | 22/55 | 1.45 (0.79-2.64) | 1.49 (0.81-2.74) | |
First | 24/56 | 2.11 (1.16-3.86) | 2.21 (1.19-4.10) |
* Using Cox proportional hazards regression. Rate of clearance for third viral load tertile (highest) taken as referent. For the analysis of combined types the observations are not independent and required a robust variance estimator. Adjusted relative rates were estimated in models that included age and sexual partners as covariates.