Table 6.
Pregnancy outcomes from the oocyte-retrieved cycles - age subgroups
| Characteristic | rFSH | hMG-HP | Chi-square | p-value |
|---|---|---|---|---|
| Total cycles started | ||||
| (≤35 years) | 15422 | 5142 | ||
| (≥36 years) | 7243 | 2823 | ||
| Number of total cycles with oocytes retrieved | ||||
| (≤35 years) | 15,293 (99.16%) | 5,137 (99.90%) | 32.55 | <0.0001 |
| (≥36 years) | 7174 (99.05%) | 2821 (99.93%) | 22.55 | <0.0001 |
| Cycles with positive pregnancy test as percent of cycles started | ||||
| (≤35 years) | 5,440 (35.27%) | 1,741 (33.86%) | 3.40 | 0.0651 |
| (≥36 years) | 2157 (29.78%) | 812 (28.76%) | 1.01 | 0.3150 |
| Cycles with positive pregnancy test as percent of cycles with oocyte retrieved | ||||
| (≤35 years) | 5,438 (35.56%) | 1,739 (33.85%) | 4.91 | 0.0267 |
| (≥36 years) | 2157 (30.07%) | 812 (28.78%) | 1.60 | 0.2065 |
| Any clinical pregnancy with positive pregnancy test | ||||
| (≤35 years) | 5302 (97.50%) | 1739 (100%) | 44.33 | <0.0001 |
| (≥36 years) | 2121 (98.33%) | 811 (99.88%) | 11.45 | 0.0007 |
| Any clinical pregnancy as percent of cycles with oocyte retrieved | ||||
| (≤35 years) | 5302 (34.67%) | 1739 (33.85%) | 1.14 | 0.2864 |
| (≥36 years) | 2121 (29.57%) | 811 (28.75%) | 0.65 | 0.4197 |
| Pregnancies ending in spontaneous abortion as percent of cycles with oocyte retrieved† | ||||
| (≤35 years) | 860 (6.00%) | 297 (5.79%) | 0.30 | 0.5841 |
| (≥36 years) | 443 (6.48%) | 181 (6.43%) | 0.0071 | 0.9329 |
Note: Cycles with positive pregnancy test were defined as cycles with a biochemical pregnancy and any clinical pregnancy. Clinical pregnancies were defined based on data entries 'clinical pregnancy', 'ongoing pregnancy', 'live birth', and 'spontaneous abortion'. Pregnancies ending in spontaneous abortion were defined as those with data entries 'spontaneous abortion' and 'miscarriage'
† Due to lack of data on this outcome, only data for Germany and Denmark were considered here to calculate the percentage (N = 21,160 for rFSH subgroup; N = 7,940 for hMG-HP subgroup).