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. Author manuscript; available in PMC: 2011 Jul 15.
Published in final edited form as: J Immunol. 2010 Jun 18;185(2):818–821. doi: 10.4049/jimmunol.1000724

FIGURE 4.

FIGURE 4

Aim2 responds to cytosolic bacteria. Control or Aim2 shRNA expressing NLRP3/NLRC4DKO (A) or WT macrophages (B) were generated by retroviral transduction and infected with L. monocytogenes at a multiplicity of infection of 10, and IL-1β secretion was determined after 4 h. C, Control or Aim2 shRNA expressing NLRP3/NLRC4DKO macrophages were infected with Francisella novicida for 8 h, and IL-1β secretion was determined. *p < 0.05.