Table 4.
Adjusted odds ratios (95% confidence intervals) for below reference semen quality parameter associated with an interquartile range increase in urinary BPA concentration. Adjusted for specific gravity, age, BMI, abstinence period, current smoking, and time of urine sample.
| Semen Quality Parameter | 1) BPA measure from same day as semen sample only (n=190)a,d | 2) Geometric Mean BPA from all participants (n=190)b,d | 3) Geometric mean BPA from men with ≥2 BPA measures (n=78)c,d | 4) BPA from same day as semen among men with ≥2 BPA measures (n=78)a,d |
|---|---|---|---|---|
| Odds Ratio (95%CI) | Odds Ratio (95%CI) | Odds Ratio (95%CI) | Odds Ratio (95%CI) | |
| Total Sperm Count (<40 × 106) | 1.20 (0.71, 2.03) | 0.98 (0.57, 1.68) | 0.30 (0.04, 2.69) | 1.50 (0.36, 6.22) |
| Sperm Concentration (<20 million/mL) | 1.47 (0.85, 2.54) | 1.21 (0.69, 2.11) | 0.37 (0.05, 2.63) | 1.18 (0.35, 3.94) |
| Sperm Motility (<50 % motile sperm) | 1.23 (0.83, 1.80) | 0.96 (0.63, 1.46) | 0.74 (0.33, 1.64) | 1.54 (0.83, 2.84) |
| Sperm Morphology (<4% normal) | 1.25 (0.77, 2.06) | 1.01 (0.60, 1.72) | 0.98 (0.35, 2.70) | 1.70 (0.73, 3.95) |
a
Among men with urine sample from same visit as blood (hormone) sample only. N=190.
b
Geometric mean of up to 3 repeated urine samples per subject, some of which were collected months after semen sample. N=190.
c
Geometric mean value among men with at least 2 urine samples. N=78.
d
Ln-transformations of bisphenol A concentration were used in the models.