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(A) A voided urine specimen contained few groups of tumor cells consistent with high-grade UC (Papanicolaou stain). (B) Atypical cells showed polysomies for chromosomes 3 (red), 7 (green), and 17 (aqua) (FISH). In this case, 16 of 25 cells analyzed showed an abnormal result, indicative of a positive FISH result. Clinical follow-up showed carcinoma in situ.
