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. Author manuscript; available in PMC: 2010 Nov 30.
Published in final edited form as: J Immunol. 2007 Mar 15;178(6):3924–3931. doi: 10.4049/jimmunol.178.6.3924

FIGURE 2.

FIGURE 2

Early treatment with CTLA4Ig plus anti-CD154 but not late treatment prevents the induction of IgM and IgG1 antibody responses to the major timothy grass pollen allergen Phl p 5. Serum samples, collected at day 0, 21, and 42 after primary immunization were analyzed for Phl p 5-specific IgM and IgG1 antibodies by ELISA. Antibody levels are displayed as box-and-whiskers plots, * indicates a significant reduction (p<0.05) compared to the untreated but sensitized group A.