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Treatment with CTLA4Ig and/or anti-CD154 reduces lymphoproliferative responses to Phl p 5. T cell proliferation was measured at day 100 in spleen cell cultures after in vitro stimulation with timothy grass pollen allergens Phl p 5 (black bars) or Phl p 2, an immunologically unrelated grass pollen allergen (negative control) (grey bars). The bars represent the mean stimulation indices (SI±SD) for the different groups of mice.
