Table 3. Combination index (CI) value of the combination therapy of AZD6244 and MK2206 at the ratio of 5∶1.
Cell Lines | 50% CI | 75% CI |
H23 | 0.03 | 0.19 |
HCC193 | 0.05 | 0.03 |
HCC827 | 0.05 | 0.06 |
H2023 | 0.06 | 0.13 |
H1693 | 0.06 | 0.17 |
H1299 | 0.06 | 0.02 |
H1703 | 0.06 | 0.01 |
HCC44 | 0.09 | 0.15 |
H1993 | 0.09 | 0.17 |
H125 | 0.12 | 0.06 |
A549 | 0.12 | 0.32 |
Calu1 | 0.13 | 0.10 |
H661 | 0.13 | 0.20 |
H515 | 0.16 | 0.22 |
H2347 | 0.17 | 0.14 |
H3122 | 0.2 | 0.28 |
H157 | 0.24 | 0.19 |
H226 | 0.24 | 1.41 |
H1792 | 0.24 | 0.48 |
H460 | 0.31 | 0.42 |
H2009 | 0.45 | 0.44 |
H1650 | 0.52 | 0.57 |
H2882 | 0.67 | 0.81 |
H838 | 0.80 | 0.20 |
H1975 | 0.85 | 0.39 |
H196 | 0.97 | 1.44 |
H522 | 1.01 | 0.88 |
Calu6 | 2.48 | 1.30 |