Table 6.
In vitro antibacterial susceptibility pattern of bacterial isolates recovered from ocular specimens obtained from (n = 2611) eyes with bacterial ocular infections
| Amikacin | Tobramycin | Gentamicin | Cefaolzin | Cephotaxime | Cetazidime | Norfloxacin | Ciprofloxacin | Ofloxacin | Gatifloxacin | Moxifloxacin | Chloramphenicol | Vancomycin | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gram-positive cocci | 52 (810/1553) | 44 (686/1553) | 48 (740/1553) | 92 (1426/1553) | 83 (1293/1553) | 63 (984/1553) | 81 (1257/1553) | 82 (1273/1553) | 87 (1352/1553) | 94 (206/220) | 99 (218/220) | 95 (1474/1553) | 99 (1539/1553) |
| Sta. aureus | 99 (691/697) | 79 (551/697) | 80 (555/697) | 89 (619/697) | 80 (555/697) | 40 (277/697) | 87 (606/697) | 88 (610/697) | 89 (617/697) | 96 (101/105) | 98 (103/105) | 99 (690/697) | 100 (697/697) |
| CoNS | 73 (119/162) | 33 (53/162) | 41 (66/162) | 75 (122/162) | 41 (67/162) | 22 (36/162) | 41 (67/162) | 41 (67/162) | 43 (69/162) | 95 (20/21) | 100 (21/21) | 70 (113/162) | 100 (162/162) |
| Str. pneumoniae | 0 (0/578) | 12 (69/578) | 17 (99/578) | 99 (573/578) | 97 (561/578) | 97 (561/578) | 84 (485/578) | 85 (492/578) | 96 (554/578) | 92 (73/79) | 100 (79/79) | 97 (561/578) | 99 (570/578) |
| S. pyogenes | 0 (0/42) | 10 (4/42) | 17 (7/42) | 100 (42/42) | 95 (40/42) | 95 (40/42) | 83 (35/42) | 91 (38/42) | 95 (40/42) | 80 (4/5) | 100 (5/5) | 95 (40/42) | 95 (40/42) |
| S. viridans | 0 (0/74) | 12 (9/74) | 18 (13/74) | 99 (73/74) | 95 (70/74) | 95 (70/74) | 87 (64/74) | 89 (66/74) | 97 (72/74) | 80 (8/10) | 100 (10/10) | 95 (70/74) | 95 (70/74) |
| Gram-positive bacilli | 90 (211/234) | 58 (136/234) | 49 (114/234) | 92 (214/234) | 86 (202/234) | 86 (202/234) | 43 (101/234) | 61 (142/234) | 90 (211/234) | 100 (8/8) | 100 (8/8) | 49 (114/234) | 90 (211/234) |
| Bacillus spp | 92 (25/27) | 59 (16/27) | 48 (13/27) | 93 (25/27) | 48 (13/27) | 48 (13/27) | 37 (10/27) | 48 (13/27) | 92.6 (25/27) | 100 (4/4) | 100 (4/4) | 48 (13/27) | 92.6 (25/27) |
| Corynebacterium spp. | 90 (186/207) | 58 (120/207) | 49 (101/207) | 91 (189/207) | 91 (189/207) | 91 (189/207) | 44 (91/207) | 62 (129/207) | 90 (186/207) | 100 (4/4) | 100 (4/4) | 49 (101/207) | 90 (186/207) |
| Gram-negative cocci | 99 (168/169) | 82 (138/169) | 81 (136/169) | 9 (15/169) | 86 (146/169) | 91 (154/169) | 94 (159/169) | 94 (159/169) | 99 (168/169) | 95 (19/20) | 90 (18/20) | 88 (149/169) | 7 (12/169) |
| M. lacunata | 100 (48/48) | 96 (46/48) | 96 (46/48) | 19 (9/48) | 83 (40/48) | 92 (44/48) | 96 (46/48) | 96 (46/48) | 98 (47/48) | 100 (7/7) | 86 (6/7) | 96 (46/48) | 19 (9/48) |
| Ne. gonorrhea | 100 (11/11) | 73 (8/11) | 73 (8/11) | 0 (0/11) | 82 (9/11) | 82 (9/11) | 91 (10/11) | 91 (10/11) | 100 (11/11) | 100 (2/2) | 100 (2/2) | 73 (8/11) | 9 (1/11) |
| Ne. meningitides | 100 (3/3) | 67 (2/3) | 67 (2/3) | 0 (0/3) | 100 (3/3) | 100 (3/3) | 100 (3/3) | 100 (3/3) | 100 (3/3) | not done | not done | 100 (3/3) | 0 (0/3) |
| M. catarrhalis | 98.9 (93/94) | 77 (72/94) | 75 (70/94) | 6 (6/94) | 87 (82/94) | 94 (88/94) | 94 (88/94) | 94 (88/94) | 100 (94/94) | 91 (10/11) | 91 (10/11) | 87 (82/94) | 2 (2/94) |
| Acinetobacter spp. | 100 (13/13) | 77 (10/13) | 77 (10/13) | 0 (0/13) | 92 (12/13) | 77 (10/13) | 92 (12/13) | 92 (12/13) | 100 (13/13) | not done | not done | 77 (10/13) | 0 (0/13) |
| Aerobic actinomycetes | 100 (53/53) | 47 (25/53) | 47 (25/53) | 0 (0/53) | 76 (40/53) | 13 (7/53) | 47 (25/53) | 62 (33/53) | 76 (40/53) | 100 (11/11) | 91 (10/11) | 25 (13/53) | 100 (53/53) |
| No. asteroides | 100 (53/53) | 47 (25/53) | 47 (25/53) | 0 (0/53) | 76 (40/53) | 13 (7/53) | 47 (25/53) | 62 (33/53) | 75.5 (40/53) | 100 (11/11) | 90.9 (10/11) | 25 (13/53) | 100 (53/53) |
| Gram-negative bacilli | 92 (553/602) | 43 (258/602) | 45 (268/602) | 4 (24/602) | 62 (372/602) | 71 (430/602) | 79 (476/602) | 85 (509/602) | 86 (516/602) | 92 (82/89) | 79 (70/89) | 60 (360/602) | 0.66 (4/602) |
| Ps. aeruginosa | 88 (191/218) | 30 (66/218) | 33 (71/218) | 0 (0/218) | 64 (140/218) | 80 (180/218) | 82 (179/218) | 85 (186/218) | 87 (189/218) | 88 (29/33) | 79 (26/33) | 60 (131/218) | 0 (0/218) |
| Es. coli | 96 (23/24) | 13 (3/24) | 13 (3/24) | 0 (0/24) | 21 (5/24) | 25 (6/24) | 33 (8/24) | 33 (8/24) | 33 (8/24) | 67 (2/3) | 33 (1/3) | 21 (5/24) | 0 (0/24) |
| H. influenzae | 88 (79/90) | 79 (71/90) | 81 (73/90) | 16 (15/90) | 61 (55/90) | 66 (59/90) | 83 (75/90) | 86 (77/90) | 88 (79/90) | 92 (11/12) | 100 (12/12) | 61 (55/90) | 0 (0/90) |
| H. parainfluenzae | 98 (47/48) | 83 (40/48) | 88 (42/48) | 10 (5/48) | 75 (36/48) | 79 (38/48) | 85 (41/48) | 94 (45/48) | 98 (47/48) | 100 (12/12) | 100 (12/12) | 63 (30/48) | 0 (0/48) |
| H. aegypticus | 100 (15/15) | 87 (13/15) | 87 (13/15) | 7 (1/15) | 80 (12/15) | 80 (12/15) | 87 (13/15) | 100 (15/15) | 100 (15/15) | 100 (2/2) | 100 (2/2) | 80 (12/15) | 0 (0/15) |
| En. agglomerans | 100(16/16) | 25 (4/16) | 31 (5/16) | 0 (0/16) | 50 (8/16) | 63 (10/16) | 88 (14/16) | 94 (15/16) | 94 (15/16) | 100 (2/2) | 100 (2/2) | 63 (10/16) | 0 (0/16) |
| En. aerogenes | 96 (47/49) | 27 (13/49) | 23 (11/49) | 0 (0/49) | 61 (30/49) | 67 (33/49) | 78 (38/49) | 84 (41/49) | 84 (41/49) | 100 (7/7) | 71 (5/7) | 62 (30/49) | 0 (0/49) |
| En. cloacae | 100 (5/5) | 20 (1/5) | 20 (1/5) | 0 (0/5) | 40 (2/5) | 60 (3/5) | 80 (4/5) | 100 (5/5) | 100 (5/5) | not done | not done | 60 (3/5) | 0 (0/5) |
| K. ozaenae | 100 (9/9) | 44 (4/9) | 44 (4/9) | 0 (0/9) | 78 (7/9) | 78 (7/9) | 78 (7/9) | 89 (8/9) | 89 (8/9) | not done | not done | 78 (7/9) | 0 (0/9) |
| K. pneumoniae | 92 (70/76) | 28 (21/76) | 30 (23/76) | 0 (0/76) | 58 (44/76) | 63 (48/76) | 70 (53/76) | 80 (61/76) | 80 (61/76) | 91 (10/11) | 55 (6/11) | 58 (44/76) | 0 (0/76) |
| Ci. diversus | 100 (10/10) | 40 (4/10) | 40 (4/10) | 0 (0/10) | 70 (7/10) | 70 (7/10) | 90 (9/10) | 90 (9/10) | 90 (9/10) | 100 (1/1) | 100 (1/1) | 70 (7/10) | 10 (1/10) |
| Ci. freundic | 100 (7/7) | 57 (4/7) | 57 (4/7) | 14(1/7) | 71 (5/7) | 71 (5/7) | 86 (6/7) | 100 (7/7) | 100 (7/7) | 100 (1/1) | 100 (1/1) | 72 (5/7) | 14(1/7) |
| Al. faecalis | 100 (9/9) | 44 (4/9) | 44 (4/9) | 0 (0/9) | 78 (7/9) | 78 (7/9) | 78 (7/9) | 89 (8/9) | 89 (8/9) | 100 (1/1) | 0 (0/1) | 78 (7/9) | 0 (0/9) |
| Pr. mirabilis | 91 (10/11) | 27 (3/11) | 27 (3/11) | 0 (0/11) | 36 (4/11) | 36 (4/11) | 81 (9/11) | 81 (9/11) | 82 (9/11) | 100 (2/2) | 0 (0/2) | 36 (4/11) | 0 (0/11) |
| Pr. vulgaris | 100 (5/5) | 20 (1/5) | 20 (1/5) | 0 (0/5) | 40 (2/5) | 60 (3/5) | 80 (4/5) | 100 (5/5) | 100 (5/5) | not done | not done | 40 (2/5) | 0 (0/5) |
| Se. marcesens | 100 (10/10) | 60 (6/10) | 60 (6/10) | 20 (2/10) | 80 (8/10) | 80 (8/10) | 90 (9/10) | 100 (10/10) | 100 (10/10) | 100 (2/2) | 100 (2/2) | 80 (8/10) | 20 (2/10) |
| Total | 68.74 (1795/2611) | 47.6 (1243/2611) | 49.14 (1283/2611) | 64.3 (1679/2611) | 78.63 (2053/2611) | 68.06 (1777/2611) | 77.29 (2018/2611) | 81.04 (2116/2611) | 87.59 (2287/2611) | 93.68 (326/348) | 93.1 (324/348) | 80.81 (2110/2611) | 70.43 (1839/2611) |