Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model for the role and regulation of nucleotide synthesis during HR repair. Rad3 activation in response to a DSB leads to activation of the Ddb1–Cul4Cdt2 ubiquitin ligase complex. Complex activation results in Spd1 degradation, RNR activation, and subsequent increase in dNTP pools. This dNTP pool increase is required for postsynaptic gap filling during HR repair.
