Table 2.
Cox regression: Hazard ratios across quartiles of phosphate relative to eGFR in patients with CKD stages 3 to 4
| N = 1036, Phosphate Quartiles According to eGFR | All-Cause Mortality |
Cardiovascular Mortality |
||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| First quartile (low) | 1.0 | 1.0 | ||
| Second quartile | 1.6 (1.00, 2.4) | 0.05 | 1.8 (0.9, 3.7) | 0.1 |
| Third quartile | 1.6 (0.99, 2.5) | 0.06 | 2.8 (1.3, 5.9) | 0.007 |
| Fourth quartile (high) | 1.8 (1.1, 3.1) | 0.02 | 2.9 (1.3, 6.4) | 0.01 |
Analysis adjusted for age, gender, proteinuria, diabetes, hemoglobin, systolic blood pressure, current smoking status, cardiovascular disease, eGFR, renal replacement therapy, and vitamin D analog and phosphate binder use.