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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Biochim Biophys Acta. 2010 Aug 10;1801(12):1260–1273. doi: 10.1016/j.bbalip.2010.08.002

Table 1.

Summary of characterized G-protein–coupled receptors and selective binding sites for anti-inflammatory-pro-resolution lipid mediators.

ANTI-INFLAMMATORY/
PRO-RESOLUTION
LIPID MEDIATOR
RECEPTOR Kd
(nM)
Ki
(nM)
graphic file with name nihms235092t1.jpg
*

Known partial agonism or antagonism at indicated receptor. For those ligand-receptor interactions for which Kd or Ki values were not determined, their EC50 and IC50 values are indicated, which were obtained from a β-arrestin-based luminescence system and recombinant receptors, or competition binding studies at specific receptors and cellular binding sites [see [72,73,74] and text for further details]. (RPE; retinal pigment epithelium).