Table 1.
Patient Profile and Outcome
| Group 1 | Group 2 | Group 3 | |
|---|---|---|---|
| Number | 124 | 38 | 41 |
| Date began | 6/10/90 | 8/27/91 | 11/1/91 |
| FK 506 (mg/kg/d) | 0.1 | 0.05 | 0.05 |
| Prednisone (mg/d) | 20 | 20 | 20 |
| PGE1 | No | No | Yes |
| Age | 44.9 ± 1.4 | 51.9 ± 1.7 | 50.4 ± 1.6 |
| Male/female | 76/48 | 27/11 | 24/17 |
| Liver disease | |||
| Idiopathic | 16 | 3 | 6 |
| Alcoholic | 25 | 6 | 13 |
| Viral | 24 | 19 | 11 |
| Cholestasis | 29 | 5 | 4 |
| Malignancy | 17 | 5 | 4 |
| Fulminant hepatic failure | 5 | 0 | 1 |
| Miscellaneous | 8 | 0 | 2 |
| Retransplantation within 1 month | 12 | 3 | 5 |
| Death in 1 month | 4 | 1 | 2 |
| (Patients died after retransplant) | (1) | (0) | (2) |
| Graft survival at 1 month | 109 (87.9%) | 34 (89.5%) | 36 (87.8%) |
| Patient survival at 1 month | 120 (96.8%) | 37 (97.4%) | 39 (95.1%) |
| Cause of graft failure | |||
| Preservation injury | 3 | 3 | 2 |
| Technical | 8 | 1 | 3 |
| Infection | 4 | 0 | 0 |