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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: J Mol Endocrinol. 2009 Jul 20;43(6):251–261. doi: 10.1677/JME-09-0053

Figure 6.

Figure 6

Trx, TrxR, and E2 modulate H2O2 levels. MCF-7 cells were transfected with 50 pmol control, Trx, or TrxR siRNA and treated with ethanol (−E2) or 10 nM E2 (+E2) for 24 h. Cell extracts were prepared and incubated with Amplex Red to detect the levels of H2O2. Data from three independent experiments were combined and are expressed as the mean±S.E.M. ANOVA was used to detect significant differences in the levels of H2O2 in the presence of E2 (*P≤0.05) or in response to Trx or TrxR siRNA (#P≤0.05).

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