Table 2. QTL association analysis of common SNPs and CCT in Caucasian POAG patients.
| SNP | Genotype | N | CCT µm (mean±SD) |
|---|---|---|---|
|
rs3738360 |
TT |
78 |
550.6±38.0 |
| |
GT |
14 |
545.5±30.9 |
| |
GG |
0 |
- |
| |
Total |
92 |
p-trend=0.64; p-adj=0.57 |
|
rs274754 |
TT |
45 |
561.3±32.4 |
| |
CT |
23 |
539.9±30.4 |
| |
CC |
18 |
545.1±48.8 |
| Total | 86 | p-trend=0.047; p-adj=0.018 |
CCT: the average measures of central corneal thickness between left and right eyes; p-adj: p value adjusting for sex and age of enrollment.