Table 1. iHCE/tHCE expression ratio (R) of selected genes determined for microarrays (RMA method) or by real-time PCR.
| Function | Symbol | Entrez gene ID | Microarray Log2 R (Adjusted p-value) | Real-time RT–PCR Log2 R (p-value) | TaqMan® gene expression assay |
|---|---|---|---|---|---|
| Hair keratin |
KRT81 |
3887 |
5.04 (1.20E-05) |
7.87 (3.16E-07) |
Hs00605559_m1 |
| Hyaluronan-mediated motility receptor |
HMMR |
3161 |
4.51 (1.39E-06) |
4.11 (5.67E-07) |
Hs00234864_m1 |
| Keratin of simple epithelia |
KRT7 |
3855 |
3.84 (1.79E-04) |
10.07 (2.42E-09) |
Hs00818825_m1 |
| Breast cancer resistance prot., stem cell related |
ABCG2 |
9429 |
2.60 (1.38E-05) |
6.43 (1.44E-08) |
Custom-made* |
| MDR1; drug efflux pump |
ABCB1 |
5243 |
1.54 (1.73E-03) |
8.63 (1.04E-07) |
Custom-made* |
| Protein phosphatase regulatory subunit |
SAPS3 |
55291 |
0.00 (9.93E-01) |
1.09 (1.01E-03) |
Hs00217759_m1 |
| Pore forming claudin |
CLDN15 |
24146 |
−0.53 (4.30E-03) |
0.81 (2.08E-02) |
Hs00204982_m1 |
| Receptor for hyaluronic acid |
CD44 |
960 |
−0.99 (8.85E-03) |
−0.43 (1.98E-01) |
Hs00153304_m1 |
| MRP5; drug efflux pump |
ABCC5 |
10057 |
−1.37 (5.54E-04) |
−1.72 (2.17E-05) |
Hs00981071_m1 |
| Component of tight junction strands |
CLDN1 |
9076 |
−3.43 (8.43E-04) |
−2.33 (1.31E-03) |
Hs01076359_m1 |
| Marker for corneal epithelial differentiation |
KRT3 |
3850 |
−6.57 (1.23E-06) |
−20.27 (1.17E-11) |
Hs00365080_m1 |
| Marker for corneal epithelial differentiation | KRT12 | 3859 | −8.60 (5.29E-08) | −22.30 (1.34E-11) | Hs00165015_m1 |
The asterisk indicates described by Korjamo et al. [31].