Table 3. The association between patient, treatment and tumor characteristics and risk of death after diagnosis of malignant GCT of bone using Cox proportional hazards regression.
| Characteristic | Hazard ratio† | p |
|---|---|---|
| Age at diagnosis‡ | 1.41 | <0.01 |
| Year of diagnosis | 1.03 | 0.84 |
| Gender | ||
| Female | 1.00 | |
| Male | 0.73 | 0.46 |
| Race | ||
| White | 1.00 | |
| Black | 0.45 | 0.17 |
| Other | 0.55 | 0.41 |
| Stage at diagnosis | ||
| Localized | 1.00 | |
| Regional spread | 1.41 | 0.49 |
| Distant metastases | 5.20 | <0.01 |
| Stage unknown | 0.20 | 0.14 |
| Treatment | ||
| None | 1.00 | |
| Surgery | 0.99 | 0.15 |
| Radiation | 0.76 | 0.69 |
| Surgery + radiation | 1.04 | 0.94 |
†
Estimate of relative risk adjusted for all other variables in the final multivariable model (age, year of diagnosis, gender, race, stage, treatment).
‡
Hazard Ratio represents an estimate of the increase in risk of death with each increase from one 5-year age group to the next starting with and including the following age groupings (10–14 years, 15–19 years, …,>85 years)