Fig. 7.

c-Rel^−/− mice have impaired cytokine responses that can be rescued in a WT environment. (A) Cytokine responses of immunized (CPS, day 35 post-immunization) or immunized and challenged (Chall, day 5 post-challenge with 10⁶ CPS-OVA) WT and c-Rel^−/− splenocytes were assessed by ELISA. Data represent average ± standard deviation with three to four mice per group from one of two similar experiments. (B) Cytokine responses from splenocytes as described in Fig. 7(B) were measured by ELISA. Data represent average ± standard deviation for five mice per group from one representative experiment.