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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Arthritis Rheum. 2010 Jul;62(7):1921–1932. doi: 10.1002/art.27470

Figure 4. Attenuated course of serum-transferred arthritis in CXCR2−/− mice but not in other chemokine-receptor-deficient animals.

Figure 4

Serum-transferred arthritis in chemokine receptor and chemokine knockout mice was compared with that of heterozygote littermate controls (or to wild-type mice for CCR4 and CCR9 or hemizygous wild-type males for CXCR3). N=10 for CXCR2, CCR1, CCR6, CCR7, and CX3CR1; n=5 for other lines. P-values were calculated for each knockout line using area under the curve (AUC) analysis of ankle thickening over the first 20 days. The p=0.05 significance level adjusted using the Bonferroni correction was p=0.0036.