Table 2.
Groups | Superoxide dismutase (U#/mg protein) | Catalase (U#/mg protein) | Glutathione peroxidase (U#/mg protein) | TBARS | Hydroperoxides | ||
---|---|---|---|---|---|---|---|
Plasma (mM/dl) | Liver (mM/100 g tissue) | Plasma (mM/dl) | Liver (mM/100 g tissue) | ||||
Normal | 6.38a ± 0.38 | 71.16a ± 4.23 | 6.09a ± 0.42 | 0.16a ± 0.01 | 0.93a ± 0.05 | 9.29a ± 0.72 | 95.24a ± 8.10 |
Normal + CA (40 mg/kg) | 6.34a ± 0.44 | 74.88a ± 5.18 | 6.16a ± 0.33 | 0.15a ± 0.01 | 0.89a ± 0.07 | 8.64a ± 0.64 | 89.48a ± 7.61 |
Normal + OXT (200 mg/kg) | 3.43b ± 0.22 | 48.65b ± 3.09 | 2.23b ± 0.14 | 0.32b ± 0.02 | 1.64b ± 0.13 | 16.47b ± 1.5 | 142.78b ± 11.59 |
OXT (200 mg/kg) + CA (40 mg/kg) | 5.23c ± 0.23 | 63.44c ± 2.82 | 5.40c ± 0.29 | 0.18c ± 0.01 | 1.15c ± 0.09 | 10.25c ± 0.57 | 113.06c ± 9.18 |
Values are mean ± SD of six rats for each group; CA caffeic acid, OXT oxytetracycline
Values not sharing a common superscript letters (a–c) differ significantly at P < 0.05 (DMRT)
#Units of enzyme activity expressed
SOD, one unit of activity was taken as the enzyme reaction, which gave 50% inhibition of NBT reduction in 1 min; CAT, μ moles of hydrogen peroxide consumed/min/mg protein; GPx, μg of glutathione consumed/min/mg protein