Table 2. Basic and perinatal characteristics and incidence of neonatal complications among infants with LCC.
| Characteristic | LCC (n=26) | Controls (n=52) | P-value | OR | 95% CI |
|---|---|---|---|---|---|
| Basic characteristic | |||||
| Birth weight (g), mean±s.d. | 741±166 | 811±144 | NS | — | — |
| Gestational age (weeks), mean ±s.d. | 25.7±1.5 | 26.2±1.1 | NS | — | — |
| Birth weight s.d. score, mean ±s.d. | −0.48±0.78 | −0.39±0.70 | NS | — | — |
| Male gender | 13 (50%) | 23 (44%) | NS | 0.79 | 0.31–2.04 |
| Outborna | 4 (15%) | 5 (10%) | NS | 1.71 | 0.42–7.00 |
| Multiple birth | 7 (27%) | 19 (37%) | NS | 0.64 | 0.23–1.80 |
| Apgar score | |||||
| At 1 min, median (range) | 3 (1–8) | 5 (1–8) | <0.05 | — | — |
| At 5 min, median (range) | 6 (2–9) | 6 (2–9) | NS | — | — |
| Surfactant given | 20 (77%) | 35 (67%) | NS | 1.62 | 0.55–4.77 |
| On admitting NICU | |||||
| Mean arterial presssure, mean ±s.d. | 24.2±5.5 | 26.8±6.2 | NS | — | — |
| Ventilatory index, mean ±s.d. | 0.08±0.06 | 0.06±0.04 | NS | — | — |
| A-aDO2, mean ±s.d. | 382±178 | 330±197 | NS | — | — |
| Perinatal characteristic | |||||
| Maternal hypertension | 2 (8%) | 6 (12%) | NS | 0.64 | 0.12–3.41 |
| Maternal DM/GDM | 0 (0%) | 0 (0%) | NS | — | — |
| PROM | 11 (42%) | 29 (56%) | NS | 0.58 | 0.23–1.51 |
| Received antenatal steroid | 8 (31%) | 16 (31%) | NS | 1.00 | 0.36–2.77 |
| CAM | 17 (65%) | 29 (56%) | NS | 1.50 | 0.57–3.98 |
| Cesarean section | 17 (65%) | 38 (73%) | NS | 0.70 | 0.25–1.92 |
| Neonatal complications | |||||
| RDS | 12 (46%) | 21 (40%) | NS | 1.27 | 0.49–3.27 |
| Pulmonary hemorrhage | 4 (15%) | 5 (10%) | NS | 1.71 | 0.42–6.99 |
| PDA | 7 (27%) | 19 (37%) | NS | 0.64 | 0.23–1.80 |
| IVH | |||||
| Grade 1–2 | 6 (23%) | 11 (21%) | NS | 1.12 | 0.36–3.46 |
| Grade ⩾3 | 5 (19%) | 0 (0%) | <0.01 | 1.23 | 1.03–1.49 |
| NEC/gastrointestinal perforation | 1 (4%) | 0 (0%) | NS | 1.04 | 0.96–1.12 |
Abbreviations: A-aDO2, alveolar-arterial oxygen tension difference; CAM, chorioamnionitis diagnosed histologically; CI, confidence interval; DM, diabetes mellitus; GDM, gestational diabetes mellitus; IVH, intraventricular hemorrhage; LCC, late-onset circulatory collapse; NEC, necrotizing enterocolitis; NICU, neonatal intensive care unit; OR, odds ratio; PDA, patent ductus arteriosus; PROM, premature rupture of membranes; RDS, respiratory distress syndrome.
a
Outborn refers to infants born in other hospitals and transferred to our hospital.