Table 1.
Baseline Characteristics of the Individuals of the Original Inception Cohort Not Participating versus those Participating in the Study
| Variable | VTE Cases | VTE Controls | ||||||
|---|---|---|---|---|---|---|---|---|
| DVT alone | PE±DVT | |||||||
| Non- Participants (n=344) |
Participants (n=138) |
Non- Participants (n=767) |
Participants (n=94) |
p- value |
Non-Participants (n=761) |
Participants (n=133) |
p- value |
|
| Age at Time of VTE Event^ |
66.1 (44.0, 78.0) | 49.6 (35.7, 63.1) | 74.5 (62.6, 82.9) | 51.8 (41.5, 62.4) | <.001 | 71.8 (52.5, 81.4) | 55.8 (43.4, 66.1) | <.001 |
| Male | 149 (43.3%) | 77 (55.8%) | 371 (48.4%) | 50 (53.2%) | 0.06 | 364 (47.8%) | 65 (48.9%) | 0.82 |
| BMI^ | 25.1 (22.1, 28.7) | 27.3 (24.3, 30.3) | 22.9 (19.5, 26.7) | 25.9 (23.5, 29.6) | <.001 | 25.0 (22.3, 28.2) | 26.3 (23.6, 28.2) | 0.01 |
| Obese (BMI≥30) | 60 (17.4%) | 38 (27.5%) | 109 (14.2%) | 21 (22.3%) | <.001 | 111 (14.6%) | 20 (15.0%) | 0.89 |
| Death prior to VSS Study | 193 (56.1%) | - | 687 (89.6%) | - | <.001 | 344 (45.2%) | - | - |
| Liver disease | 6 (1.7%) | 0 (0.0%) | 14 (1.8%) | 1 (1.1%) | 0.43 | 8 (1.1%) | 0 (0.0%) | 0.23 |
| Lung Disease and/or Pulmonary Hypertension |
59 (17.2%) | 12 (8.7%) | 161 (21.0%) | 7 (7.4%) | <.001 | 99 (13.0%) | 9 (6.8%) | 0.04 |
| Active Malignancy | 82 (23.8%) | 9 (6.5%) | 224 (29.2%) | 3 (3.2%) | <.001 | 32 (4.2%) | 0 (0.0%) | 0.02 |
| Congestive Heart Failure and/or cardiomyopathy |
48 (14.0%) | 1 (0.7%) | 223 (29.1%) | 1 (1.1%) | <.001 | 84 (11.0%) | 0 (0.0%) | <.001 |
| Prior Varicose Veins | 88 (25.6%) | 27 (19.6%) | 189 (24.6%) | 32 (34.0%) | 0.09 | 152 (20.0%) | 16 (12.0%) | 0.03 |
| Superficial Thrombosis | 29 (8.6%) | 15 (10.9%) | 41 (5.4%) | 7 (7.4%) | 0.05 | 27 (3.6%) | 2 (1.5%) | 0.21 |
| Venous Stasis Syndrome prior to the incident VTE |
25 (7.3%) | 11 (8.0%) | 70 (9.1%) | 3 (3.2%) | 0.22 | 47 (6.2%) | 4 (3.0%) | 0.15 |
^
Median (Q1, Q3); K–W test