Figure 1. Increased MGP expression limits the development of atherosclerotic lesions.
Apoe-/-and MGPtg/wt;Apoe-/-mice were maintained on Western diet for 16 weeks.
(A-D) Mean lesion area (A), representative Oil Red O stained aortic sinus section (B), aortic lesion coverage in en face specimens (C), and representative Sudan IV stained aortas (D) of male and female Apoe-/-and MGPtg/wt;Apoe-/-mice.
Statistically significant differences were determined by the Mann-Whitney rank sum test.