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. Author manuscript; available in PMC: 2011 Aug 20.
Published in final edited form as: Circ Res. 2010 Jun 24;107(4):485–494. doi: 10.1161/CIRCRESAHA.110.219071

Figure 4. Increased MGP expression attenuates aortic expression of ALK1 and VEGF.

Figure 4

(A-C) Aortic expression of ALK2, ALK1 and VEGF in Apoe-/-and MGPtg/wt;Apoe-/-mice fed chow (CH) or Western (HF) diet, as determined by real-time PCR (A), immunoblotting with densitometry (B), and immunohistochemistry (C).

(D) Expression of ALK1 and VEGF colocalize with expression of vWF in atherosclerotic lesions from Apoe-/-and MGPtg/wt;Apoe-/-mice fed a Western diet.

Asterisks indicate statistically significant differences compared to control (Apoe-/- mice on chow). **<0.01, ***<0.001, Tukey's test.